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Adefovir Dipivoxil

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Adefovir Dipivoxil

Adefovir Dipivoxil

CAT. No.
MRL-A48001
CAS. No.
142340-99-6
Mol. F.
C20H32N5O8P
Mol. Wt.
501.48
Synonyms
NA
Chemical Name
((((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphoryl)bis(oxy))bis(methylene) bis(2,2-dimethylpropanoate)
Stock Status
Custom Synthesis
Adefovir is a nucleotide analog reverse transcriptase inhibitor (NtRTI) used primarily in the treatment of chronic hepatitis B virus (HBV) infection. Chemically, it is an acyclic nucleotide analog of adenosine monophosphate (AMP). Adefovir works by inhibiting the reverse transcriptase enzyme of HBV, thereby blocking viral replication and reducing the viral load in infected individuals. It is typically administered orally as a prodrug, adefovir dipivoxil, which is rapidly converted to adefovir in the body. Adefovir has demonstrated efficacy in suppressing HBV replication and improving liver function markers in patients with chronic HBV infection. However, prolonged use may lead to the development of drug-resistant HBV strains, necessitating careful monitoring and combination therapy approaches to minimize resistance emergence. Buy high quality Adefovir from Molsyns Research. Molsyns Research is one of the leading manufacturer and exporter of Adefovir.

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