N-Nitroso Venetoclax Impurity 1
Product Type
Impurity Standards
CAT. No.
MRL-V07005
CAS. No.
NA
Mol. F.
C45H49ClN8O8S
Mol. Wt.
897.45
Synonyms
NA
Chemical Name
2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(nitroso((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide
Stock Status
Custom Synthesis
Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Venetoclax. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Venetoclax is a BCL-2 inhibitor prescribed for the treatment of certain blood cancers, notably chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML). Operating by inhibiting the B-cell lymphoma-2 (BCL-2) protein, Venetoclax disrupts the survival mechanisms of cancer cells, triggering programmed cell death. It is often utilized in combination with other anti-cancer drugs, particularly in cases where the cancer cells exhibit the 17p deletion genetic abnormality, making them less responsive to standard treatments. Buy high quality N-Nitroso Venetoclax Impurity 1 from Molsyns Research. Molsyns Research is one of the leading manufacturer and exporter of N-Nitroso Venetoclax Impurity 1
