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N-Nitroso Pazopanib

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N-Nitroso Pazopanib

N-Nitroso Pazopanib

Product Type
Impurity Standards
CAT. No.
MRL-P56002
CAS. No.
NA
Mol. F.
C13H11ClN6O
Mol. Wt.
302.72
Synonyms
NA
Chemical Name
N-(2-Chloropyrimidin-4-yl)-N-(2,3-dimethyl-2H-indazol-6-yl)nitrous amide
Stock Status
Please Enquire
Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Pazopanib. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Pazopanib is a tyrosine kinase inhibitor used in the treatment of certain types of cancer, particularly advanced renal cell carcinoma (kidney cancer) and soft tissue sarcoma. As a targeted therapy, pazopanib interferes with the signaling pathways involved in the growth and spread of cancer cells by inhibiting specific tyrosine kinases, including vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR), and c-kit. By blocking these pathways, pazopanib helps impede angiogenesis (the formation of new blood vessels) and suppresses the tumors ability to grow and metastasize. It is administered orally and is part of a broader treatment strategy for individuals with specific types of advanced or metastatic cancers. Buy high quality N-Nitroso Pazopanib Impurity from Molsyns Research. Molsyns Research is one of the leading manufacturer and exporter of N-Nitroso Pazopanib Impurity.

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