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N-Nitroso Anagrelide

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N-Nitroso Anagrelide

N-Nitroso Anagrelide

Product Type
Impurity Standards
CAT. No.
MRL-A116009
CAS. No.
NA
Mol. F.
C11H11Cl2N3O5
Mol. Wt.
336.13
Synonyms
NA
Chemical Name
Ethyl N-(2,3-dichloro-6-nitrobenzyl)-N-nitrosoglycinate
Stock Status
Custom Synthesis
Nitrosamines can be formed through various chemical processes, including the reaction between nitrites and secondary amines in certain conditions. It is a N-Nitroso of secondary amine present in Anagrelide. Nitrosamines are part of a broader class of compounds known as N-nitroso compounds. Anagrelide, a quinazolinone derivative, inhibits phosphodiesterase activity, particularly phosphodiesterase-III, leading to decreased platelet production in the bone marrow. Its chemical structure, with a quinazolinone core and chlorine substitutions, is crucial for its pharmacological activity. Anagrelide is employed in the treatment of essential thrombocythemia, a condition characterized by elevated platelet levels, by selectively reducing platelet production. Administered orally, it is often considered when other treatments are not well-tolerated, providing a targeted approach to managing platelet counts and mitigating the risk of thrombotic events in affected individuals. Buy high quality N-Nitroso Anagrelide from Molsyns Research. Molsyns Research is one of the leading manufacturer and exporter of N-Nitroso Anagrelide

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