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Abiraterone Acetate

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Abiraterone Acetate

Abiraterone Acetate

CAT. No.
MRL-A114001
CAS. No.
154229-18-2
Mol. F.
C26H33NO2
Mol. Wt.
391.56
Synonyms
NA
Chemical Name
17-(Pyridin-3-yl)androsta-5,16-dien-3β-yl acetate (as per USP)
Stock Status
Custom Synthesis
Abiraterone acetate is a prodrug of abiraterone, an androgen biosynthesis inhibitor. Structurally, it is an acetate ester derivative of abiraterone. Chemically, abiraterone acetate is (3β)-17-(3-pyridinyl)androsta-5,16-dien-3-yl acetate. Upon oral administration, abiraterone acetate is rapidly hydrolyzed to abiraterone, the active form of the drug.Abiraterone acetate is indicated for the treatment of metastatic castration-resistant prostate cancer (mCRPC), a form of prostate cancer that has spread to other parts of the body and no longer responds to hormone therapy. Abiraterone works by inhibiting the enzyme cytochrome P450 17α-hydroxylase/C17,20-lyase (CYP17), which is involved in the synthesis of androgens (male hormones) such as testosterone. Buy high quality Abiraterone Acetate from Molsyns Research. Molsyns Research is one of the leading manufacturer and exporter of Abiraterone Acetate.

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